SBI-0640756
| CAS No. | SBI-0640756 | Cat. No. | BCP23633 |
| Name | SBI-0640756 | ||
| Synonyms | SBI 0640756;SBI0640756;SBI 756;SBI756;SBI-756; | ||
| Formula | C23H14ClFN2O2 | M. Wt | 404.82 |
| Description | SBI-0640756（SBI-756） is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex. SBI-756 also suppressed AKT and NF-κB signaling. 1) SBI-756 inhibited the growth of NRAS, BRAF, and NF1-mutant melanomas . 2) SBI-756 attenuates resistance to BRAFi and inhibits NRAS- and NF1-mutant melanomas. 3) SBI-756 delayed the onset and reduced the incidence of Nras/Ink4a melanomas | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | eIF | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.