Cambinol

  • Chemical Properties
CAS No. 14513-15-6 Cat. No. BCP28973
Name Cambinol
Synonyms SIRT 1/2 inhibitor IV; NSC112546; NSC-112546; NSC 112546; SIRT1 Inhibitor II; SIRT2 Inhibitor VI;
Formula C21H16N2O2S M. Wt 360.43
  • Biological Activity
Description Cambinol is a SIRT inhibitor. It inhibits expression of pro-inflammatory cytokines, improves survival in models of endotoxic shock and septic shock, and prevents proliferation and increases differentiation and senescence in hepatocellular carcinoma cells.
Pathways Cell Cycle/DNA Damage Epigenetics 
Targets Sirtuin 

Structure

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