PA 6

  • Chemical Properties
CAS No. 500715-03-7 Cat. No. BCP29257
Name PA 6
Synonyms PA6;Pentamidine-Analogue 6;IK1 inhibitor PA-6;1,5-Bis[4-[[imino(phenyl)methyl]amino]phenoxy]pentane;
Formula C31H32N4O2 M. Wt 492.61
  • Biological Activity
Description PA-6 is a selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. PA-6 interacts with the cytoplasmic pore region of the KIR2.1 (KCNJ2) ion channel.
Pathways Ion Channel/Membrane Transporter 
Targets Potassium Channel 

Structure

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