TCID

  • Chemical Properties
CAS No. 30675-13-9 Cat. No. BCP29983
Name TCID
Synonyms UCH 23;UCH23;UCH-23;UCH-L3 Inhibitor;4,5,6,7-tetrachloroindan-1,3-dione;
Formula C9H2Cl4O2 M. Wt 283.92
  • Biological Activity
Description TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor (IC50 = 0.6 μM). Exhibits >100-fold selectivity for UCH-L3 over UCH-L1. Diminishes glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
Pathways Cell Cycle/DNA Damage 
Targets DUB 

Structure

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