LOXO195 R racemic

  • Chemical Properties
CAS No. 1350884-56-8 Cat. No. BCP30220
Name LOXO195 R racemic
Synonyms (6RS)-LOXO 195; (6RS) LOXO-195; (6RS)-LOXO-195;LOXO 195 R racemic;LOXO-195 R racemic;
Formula C20H21FN6O M. Wt 380.43
  • Biological Activity
Description (6RS)-LOXO-195 is a potent and selective Trk tyrosine kinase inhibitor.The R racemate of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets Trk Receptor 

Structure

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