BMX-IN-1

  • Chemical Properties
CAS No. 1431525-23-3 Cat. No. BCP30306
Name BMX-IN-1
Synonyms BMX-IN1; BMX-IN 1;BMX kinase inhibitor;
Formula C29H24N4O4S M. Wt 524.59
  • Biological Activity
Description BMX-IN-1 is a selective irreversible BMX inhibitor for prostate cancer. BMX-IN-1 can covalently modifies Cys496. BMX-IN-1 inhibits the proliferation of Tel-BMX-transformed Ba/F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor's antiproliferation efficacy against prostate cancer cells.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets BTK 

Structure

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