Aminooxyacetic acid

  • Chemical Properties
CAS No. 645-88-5 Cat. No. BCP30347
Name Aminooxyacetic acid
Synonyms 2-(Aminooxy)acetic acid;AOAA;U 7524;U7524; U-7524;Hydroxylamine, O-(carboxymethyl)-;
Formula C2H5NO3 M. Wt 91.06
  • Biological Activity
Description Aminooxyacetic acid is an inhibitor of 4-aminobutyrate aminotransferase (GABA-T). AOAA is also a general inhibitor of pyridoxal phosphate (PLP)-dependent enzymes (this includes GABA-T). It functions as an inhibitor by attacking the Schiff base linkage between PLP and the enzyme, forming oxime type complexes.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets GABA Receptor 

Structure

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