VU6012962
| CAS No. | VU6012962 | Cat. No. | BCP30357 |
| Name | VU6012962 | ||
| Synonyms | VU-6012962; VU 6012962; | ||
| Formula | C21H19F3N4O4 | M. Wt | 448.40 |
| Description | VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) that achieves exposure in cerebral spinal fluid (CSF) 2.5x above the in vitro IC50 at minimum effective doses (MEDs) of 3 mg/kg in preclinical anxiety models. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | mGluR | ||
Structure
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