Soblidotin
| CAS No. | 149606-27-9 | Cat. No. | BCP30677 |
| Name | Soblidotin | ||
| Synonyms | TZT-1027; TZT 1027; TZT1027;Auristatin PE; | ||
| Formula | C39H67N5O6 | M. Wt | 701.99 |
| Description | Soblidotin is a dolastatin-10 derivative. Soblidotin inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis. TZT-1027 showed increased antitumor activity when combined with gemcitabine in animal models. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Microtubule | ||
Structure
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