FAUC-365
| CAS No. | 474432-66-1 | Cat. No. | BCP30764 |
| Name | FAUC-365 | ||
| Synonyms | FAUC 365; FAUC365; | ||
| Formula | C23H25Cl2N3OS | M. Wt | 462.43 |
| Description | FAUC-365 is a dopamine D3 receptor antagonist (Ki = 0.5 nM).It is selective for dopamine D3 receptors over dopamine D1, D2L, D2S, and D4 receptors (Kis = 8.8, 3.6, 2.6, and 0.34 µM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT2 (Kis = 0.36 and 2 µM, respectively). FAUC-365 (1-10 mg/kg) prevents memory impairment in the novel object recognition test in dopamine transporter knockdown (DAT-KD) mice when administered prior to object learning. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Dopamine Receptor | ||
Structure
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