Ralinepag

  • Chemical Properties
CAS No. 1187856-49-0 Cat. No. BCP30843
Name Ralinepag
Synonyms APD-811; APD 811; APD811;
Formula C23H26ClNO5 M. Wt 431.91
  • Biological Activity
Description Ralinepag, also known as APD-811, is an orally available agonist of the prostacyclin (IP) receptor, is an investigational drug candidate internally discovered and developed by Arena and intended for the treatment of vasospastic diseases, such as Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, which elicits a potent vasodilation and inhibition of platelet aggregation when binding to this receptor.
Pathways GPCR/G Protein 
Targets Prostaglandin Receptor 

Structure

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