Solabegron
| CAS No. | 252920-94-8 | Cat. No. | BCP31054 |
| Name | Solabegron | ||
| Synonyms | GW-427353; GW 427353; GW427353; GW-427,353; GW 427,353; GW427,353; | ||
| Formula | C23H23ClN2O3 | M. Wt | 410.89 |
| Description | Solabegron, also known as GW-427,353, is a selective agonist for the β3 adrenergic receptor. It is being developed for the treatment of overactive bladder and irritable bowel syndrome. It has been shown to produce visceral analgesia by releasing somatostatin from adipocytes. Solabegron decreases excitability of human enteric neurons via release of somatostatin. Solabegron evokes bladder relaxation and increases micturition reflex threshold in the dog. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Adrenergic Receptor | ||
Structure
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