Etretinate

  • Chemical Properties
CAS No. 54350-48-0 Cat. No. BCP31125
Name Etretinate
Synonyms HSDB 7185; HSDB7185; HSDB-7185; NSC 297936; NSC297936; NSC-297936; Ro 10-9359; Ro 10 9359; Ro109359;
Formula C23H30O3 M. Wt 354.49
  • Biological Activity
Description Etretinate is a synthetic oral retinoid that is a prodrug of acitretin. Etretinate activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells. Etretinate is no longer commercially available in the U.S. due to the extended potential for teratogenic effects related to its long half-life.
Pathways Protease/Metabolic Enzyme 
Targets RAR/RXR 

Structure

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