Pregnanolone

CAS No.	128-20-1	Cat. No.	BCP31318
Name	Pregnanolone
Synonyms	Eltanolone; Kabi-2213; Kabi 2213; Kabi2213; SKF 6455; SKF6455;3a5b-Pregnanolone;
Formula	C21H34O2	M. Wt	318.49

Description	Pregnanolone is a cell membrane modulator potentially for the treatment of pain. Pregnanolone is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects. It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for that reason was never marketed.
Pathways	Hormone Pathay
Targets	Progesterone Receptor

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