Pregnanolone New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 128-20-1 | Cat. No. | BCP31318 |
| Name | Pregnanolone | ||
| Synonyms | Eltanolone; Kabi-2213; Kabi 2213; Kabi2213; SKF 6455; SKF6455;3a5b-Pregnanolone; | ||
| SMILES | CC(=O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C | ||
| Chemical Name | |||
| Formula | C21H34O2 | M. Wt | 318.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pregnanolone is a cell membrane modulator potentially for the treatment of pain. Pregnanolone is an endogenous neurosteroid that is biosynthesized from progesterone. It is a positive allosteric modulator of the GABAA receptor, as well as a negative allosteric modulator of the glycine receptor, and is known to have sedative, anxiolytic, anesthetic, and anticonvulsant effects. It was investigated for clinical use as a general anesthetic, but produced unwanted side effects such as convulsions on occasion, and for that reason was never marketed. | ||
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