Imetit Dihydrobromide

  • Chemical Properties
CAS No. 32385-58-3 Cat. No. BCP31622
Name Imetit Dihydrobromide
Synonyms
Formula C6H12Br2N4S M. Wt 332.06
  • Biological Activity
Description Imetit dihydrobromide is a hydrobromide salt obtained by reaction of imetit with two equivalents of hydrobromic acid. An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration. It has a role as a H4-receptor agonist and a H3-receptor agonist. It contains an imetit(2+).
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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