Aticaprant

  • Chemical Properties
CAS No. 1174130-61-0 Cat. No. BCP32123
Name Aticaprant
Synonyms CERC-501; LY-2456302;CERC501; LY2456302;CERC 501; LY 2456302;
Formula C26H27FN2O2 M. Wt 418.50
  • Biological Activity
Description Aticaprant, also known as JNJ-67953964, LY-2456302 and CERC-501, is a potent, selective, short-acting antagonist of the κ-opioid receptor (KOR) (Ki = 0.81 nM vs. 24.0 nM and 155 nM for the μ-opioid receptor (MOR) and δ-opioid receptor (DOR).
Pathways Neuro Signaling Pathway Hormone Pathay GPCR/G Protein 
Targets Opioid Receptor 

Structure

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