NTP42

  • Chemical Properties
CAS No. 2055599-51-2 Cat. No. BCP32720
Name NTP42
Synonyms NTP 42;NTP-42;
Formula C25H23F2N3O5S M. Wt 515.53
  • Biological Activity
Description NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. NTP42 can be used for the treatment of pulmonary arterial hypertension (PAH).
Pathways GPCR/G Protein 
Targets Prostaglandin Receptor 

Structure

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