Dantrolene

  • Chemical Properties
CAS No. 7261-97-4 Cat. No. BCP33078
Name Dantrolene
Synonyms Dantrolenum; Dantrium; Dantrolenum;
Formula C14H10N4O5 M. Wt 314.26
  • Biological Activity
Description Dantrolene is a hydantoin derivative and direct-acting skeletal muscle relaxant. Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1, and decreasing intracellular calcium concentration. Ryanodine receptors mediate the release of calcium from the sarcoplasmic reticulum, an essential step in muscle contraction.
Pathways Ion Channel/Membrane Transporter 
Targets Calcium Channel 

Structure

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