Gabazine
| CAS No. | 105538-73-6 | Cat. No. | BCP33110 |
| Name | Gabazine | ||
| Synonyms | SR95531; SR 95531; SR-95531; | ||
| Formula | C15H17N3O3 | M. Wt | 287.31 |
| Description | Gabazine is a selective, competitive GABAA receptor antagonist. Displaces [3H]-GABA from rat brain membranes with a Ki of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl- currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway | ||
| Targets | GABA Receptor | ||
Structure
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