Bigelovin

  • Chemical Properties
CAS No. 3668-14-2 Cat. No. BCP34451
Name Bigelovin
Synonyms
Formula C17H20O5 M. Wt 304.34
  • Biological Activity
Description Bigelovin, a sesquiterpene lactone isolated from Inula helianthus-aquatica, is a selective retinoid X receptor α agonist. Bigelovin suppresses tumor growth through inducing apoptosis and autophagy via the inhibition of mTOR pathway regulated by ROS generation.
Pathways Protease/Metabolic Enzyme 
Targets RAR/RXR 

Structure

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