BI-749327
| CAS No. | 2361241-23-6 | Cat. No. | BCP34713 |
| Name | BI-749327 | ||
| Synonyms | BI749327;BI 749327; | ||
| Formula | C23H21F3N4O2 | M. Wt | 442.43 |
| Description | BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | TRP Channel | ||
Structure
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