ML406
| CAS No. | 774589-47-8 | Cat. No. | BCP35591 |
| Name | ML406 | ||
| Synonyms | ML-406; ML 406; | ||
| Formula | C20H20N2O4 | M. Wt | 352.39 |
| Description | ML406 is an iInhibitor of aminotranferase BioA, the enzyme that catalyzes the second-to-last step of biotin synthesis in Mycobacterium tuberculosis (TB). ML406 has an IC50 of 155 nM and an EC50 of 9.3 μM with best cellular activity tested in a TB strain with limited biotin formation relative to wild type confirming mechanism of action. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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