MSAB
| CAS No. | 173436-66-3 | Cat. No. | BCP35746 |
| Name | MSAB | ||
| Synonyms | Methyl 3-(4-methylbenzenesulfonamido)benzoate; | ||
| Formula | C15H15NO4S | M. Wt | 305.35 |
| Description | MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Wnt | ||
Structure
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