MK-212
CAS No. | 64022-27-1 | Cat. No. | BCP37027 |
Name | MK-212 | ||
Synonyms | MK 212; MK-212; | ||
Formula | C8H11ClN4 | M. Wt | 198.65 |
Description | MK-212 is a 5HT2C-receptor agonist. A dose-dependent the effect of 5HT2C-receptor agonist MK-212 on mouse behavior was demonstrated. Intraperitoneal injection of MK-212 in high doses (0.5 and 1.0 mg/kg) increased blood level of corticosterone in mice and reduced their motor activity. In low doses of 0.1 and 0.2 mg/kg, the agonist reduced anxiety, but had no effect on motor activity. It is hypothesized that low doses of MK-212 exhibited anxiolytic activity in mice. | ||
Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
Targets | 5 HT Receptor/Serotonin Receptor |
Structure
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