BMS453

  • Chemical Properties
CAS No. 166977-43-1 Cat. No. BCP37819
Name BMS453
Synonyms BMS 453; BMS-453; BMS 189453; BMS-189453; BMS189453;
Formula C27H24O2 M. Wt 380.48
  • Biological Activity
Description BMS453 is a retinoic acid receptor β (RARβ) agonist in vivo and also RARα and RARγ antagonist in vitro. BMS453 inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.
Pathways Protease/Metabolic Enzyme 
Targets RAR/RXR 

Structure

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