PD-118057
| CAS No. | 313674-97-4 | Cat. No. | BCP39203 |
| Name | PD-118057 | ||
| Synonyms | PD 118057; PD118057; | ||
| Formula | C21H17Cl2NO2 | M. Wt | 386.27 |
| Description | PD 118057 is a human ether-a-go-go (hERG) KV11.1 potassium channel activator, with no major effect on INa, ICa/L, IK1 and IKs currents. PD-118057prevents and reverses QT interval prolongation; Compounds such as PD-118057 may offer new approach in the treatment of delayed repolarization conditions, which occur in inherited or acquired long QT syndrome and congestive heart failure. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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