U-46619
| CAS No. | 56985-40-1 | Cat. No. | BCP39866 |
| Name | U-46619 | ||
| Synonyms | U 46619;U46619; | ||
| Formula | C21H34O4 | M. Wt | 350.49 |
| Description | U46619 is a PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). U46619 potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. It activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Prostaglandin Receptor | ||
Structure
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