MRK-016

  • Chemical Properties
CAS No. 342652-67-9 Cat. No. BCP40367
Name MRK-016
Synonyms MRK 016;MRK016;
Formula C17H20N8O2 M. Wt 368.39
  • Biological Activity
Description MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM. It has nootropic properties. MRK-016 can produce rapid, ketamine-like antidepressant effects in animal models of depression.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway 
Targets GABA Receptor 

Structure

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