NS8593 hydrochloride
| CAS No. | 875755-24-1 | Cat. No. | BCP41256 |
| Name | NS8593 hydrochloride | ||
| Synonyms | NS8593 HCl; NS-8593 HCl;NS 8593 hydrochloride; | ||
| Formula | C17H17N3.ClH | M. Wt | 299.8 |
| Description | NS8593 HCl is a selective KCa2 (SK) channel negative modulator. NS8593 inhibits SK channel currents (Kd values are 0.42, 0.6 and 0.73 μM for SK1, SK2 and SK3 respectively at 0.5 μM Ca2+). It exhibits selectivity for SK channels over KCa1.1 (BK), KCa3.1 (IK), Kv, Nav and Cav channels. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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