Viloxazine hydrochloride

CAS No.	35604-67-2	Cat. No.	BCP41580
Name	Viloxazine hydrochloride
Synonyms	Viloxazine HCl; ICI 58,834; ICI-58,834; ICI58,834; ICI 58834; ICI-58834; ICI58834; SPN-812; SPN 812; SPN812;
Formula	C13H20ClNO3	M. Wt	273.76

Description	Viloxazine is aselective norepinephrine reuptake inhibitor (NRI). Viloxazine was approved for medical use in the United States in April 2021 to treat attention deficit hyperactivity disorder (ADHD). Viloxazine, like imipramine, inhibited norepinephrine reuptake in the hearts of rats and mice; unlike imipramine, it did not block reuptake of norepinephrine in either the medullae or the hypothalami of rats. As for serotonin, while its reuptake inhibition was comparable to that of desipramine (i.e., very weak), viloxazine did potentiate serotonin-mediated brain functions in a manner similar to amitriptyline and imipramine, which are relatively potent inhibitors of serotonin reuptake. Unlike any of the other drugs tested, it did not exhibit any anticholinergic effects.
Related Products	46817-91-8（Viloxazine） 56287-63-9（(R)-Viloxazine Hydrochloride） 56287-61-7（(S)-Viloxazine Hydrochloride）
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Dopamine Receptor

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