BMS 195614
| CAS No. | 253310-42-8 | Cat. No. | BCP44394 |
| Name | BMS 195614 | ||
| Synonyms | BMS195614;BMS-195614; | ||
| Formula | C29H24N2O3 | M. Wt | 448.51 |
| Description | BMS 195614 is a neutral RAR α-selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding. BMS 195614 moderately decreases SMRT binding to RAR and agonist-induced coactivator (CoA) recruitment. Also it is a derivative of retinoic acid. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | RAR/RXR | ||
Structure
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