RM-018
| CAS No. | 2641993-55-5 | Cat. No. | BCP48790 |
| Name | RM-018 | ||
| Synonyms | RM018;RM 018; | ||
| Formula | C56H72N8O8 | M. Wt | 985.24 |
| Description | RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [“RAS(ON)”] state of KRASG12C. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Ras/Rho | ||
Structure
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