DSG3-CAART

  • Chemical Properties
CAS No. DSG3-CAART Cat. No. BCP49531
Name DSG3-CAART
Synonyms Desmoglein 3 chimeric autoantibody receptor T cells;
Formula M. Wt
  • Biological Activity
Description DSG3-CAART specifically lysed human anti-DSG3 B cells from PV patients and demonstrated activity consistent with a threshold dose in vivo, resulting in decreased target cell burden, decreased serum and tissue-bound autoantibodies, and increased DSG3-CAART engraftment.
Pathways Others Pathway 
Targets Others 

Structure

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