Fluvastatin
| CAS No. | 93957-54-1 | Cat. No. | BCP08213 |
| Name | Fluvastatin | ||
| Synonyms | |||
| Formula | C24H26FNO4 | M. Wt | 411.47 |
| Description | Fluvastatin is an HMGCR (HMG-CoA reductase) inhibitor. The compound is described to inhibit cell proliferation, illicit apoptosis, and protect against oxidative stress. Human hepatocellular carcinoma cell (HCC) studies indicate that Fluvastatin induces G2/M phase arrest. In the presence of Fluvastatin, HCC cells show a decrease of Bcl-2 and procaspase-9 expression, and an increase in Bax, cleaved caspase-3, and cytochrome c. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | HMGCR | ||
Structure
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