Ifosfamide

  • Chemical Properties
CAS No. 3778-73-2 Cat. No. BCP06596
Name Ifosfamide
Synonyms Isophosphamide; Iphosphamide; Isofosfamide; Ifosfamid;
Formula C7H15Cl2N2O2P M. Wt 261.09
  • Biological Activity
Description Ifosfamide is a synthetic analogue of the nitrogen mustard cyclophosphamide with antineoplastic activity. Ifosfamide alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes.
Pathways Cell Cycle/DNA Damage 
Targets DNA Alkylator/Crosslinker 

Structure

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