Bevacizumab

  • Chemical Properties
CAS No. 216974-75-3 Cat. No. BCP07998
Name Bevacizumab
Synonyms Avastin;Anti-vegf monoclonal antibody;Rhumab-vegf;
Formula C6638H10160N1720O2108S44 M. Wt 149196.82
  • Biological Activity
Description Bevacizumab is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor A (VEGF-A).VEGF-A is a growth factor protein that stimulates angiogenesis in a variety of diseases, especially in cancer. Bevacizumab was the first available angiogenesis inhibitor in the United States.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets VEGFR 
  • Publications Citing

Structure

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