BMS-564929

  • Chemical Properties
CAS No. 627530-84-1 Cat. No. BCP21121
Name BMS-564929
Synonyms BMS 564929; BMS564929;
Formula C14H12ClN3O3 M. Wt 305.72
  • Biological Activity
Description BMS-564929 is a highly potent, orally active, nonsteroidal tissue selective androgen receptor (AR) modulator. BMS-564929 is a subnanomolar AR agonist in vitro, is highly selective for the AR vs. other steroid hormone receptors, and exhibits no significant interactions with SHBG or aromatase. Dose response studies in castrated male rats show that BMS-564929 is substantially more potent than testosterone (T) in stimulating the growth of the levator ani muscle, and unlike T, highly selective for muscle vs. prostate.
Pathways Hormone Pathay 
Targets Androgen Receptor  

Structure

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