Pemirolast potassium

  • Chemical Properties
CAS No. 100299-08-9 Cat. No. BCP21138
Name Pemirolast potassium
Synonyms Pemirolast potassium salt;BMY 26517; TWT8152; BMY 26517;TWT-8152; BMY 26517; TWT8152;
Formula C10H7KN6O M. Wt 266.31
  • Biological Activity
Description Pemirolast Potassium is the potassium salt form of pemirolast, a pyrimidinone derivative with antiallergic property. Pemirolast potassium exerts its action by blocking the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, histamine and leukotrienes, which are involved in the allergic process. Pemirolast potassium also prevents inflammatory mediator release from eosinophils.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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