SB 243213 dihydrochloride

  • Chemical Properties
CAS No. 200940-23-4 Cat. No. BCP07224
Name SB 243213 dihydrochloride
Synonyms SB243213A;SB 243213; SB-243213; SB243213; SB 243213 DiHCl;
Formula C22H19F3N4O2.2HCl M. Wt 428.41
  • Biological Activity
Description SB 243213 dihydrochloride is a selective 5-HT2C inverse agonist (pKb = 9.8). It displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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