ZM323881
| CAS No. | 324077-30-7 | Cat. No. | BCP06446 |
| Name | ZM323881 | ||
| Synonyms | ZM-323881;ZM 323881; | ||
| Formula | C22H18FN3O2 | M. Wt | 375.4 |
| Description | ZM323881 selectively inhibits VEGFR-2 (IC50 = 2 nM) over VEGFR-1 and a range of other receptor tyrosine kinases such as PDGFRβ, FGFR1, EGFR and erbB2 (IC50 > 50 μM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation in vitro (IC50 = 8 nM). | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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