Amlodipine besylate

CAS No.	111470-99-6	Cat. No.	BCP21993
Name	Amlodipine besylate
Synonyms	Amlodipine benzenesulfonate;
Formula	C20H25ClN2O5.C6H6O3S	M. Wt	567.05

Description	Amlodipine Besylate is the besylate salt of amlodipine, a synthetic dihydropyridine with antihypertensive and antianginal effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
Pathways	Ion Channel/Membrane Transporter
Targets	Calcium Channel

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