Pemetrexed disodium hydrate
| CAS No. | 357166-30-4 | Cat. No. | BCP22709 |
| Name | Pemetrexed disodium hydrate | ||
| Synonyms | LY-231514 Disodium Hydrate；Pemetrexed disodium 2.5 hydrate；Pemetrexed disodium hemipenta hydrate；Pemetrexed sodium hydrate; | ||
| Formula | 2(C20H19N5Na2O6).5(H2O) | M. Wt | 1032.83 |
| Description | Pemetrexed Disodium Hydrate is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DHFR | ||
Structure
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