Tropisetron

  • Chemical Properties
CAS No. 89565-68-4 Cat. No. BCP27620
Name Tropisetron
Synonyms SDZ-ICS-930;ICS-205930; ICS 205930; ICS205930; ICS 205-930; ICS-205-930;
Formula C17H20N2O2 M. Wt 284.35
  • Biological Activity
Description Tropisetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. The drug is available in a 5 mg oral preparation or in 2 mg intravenous form. It is marketed by Novartis in Europe, Australia, New Zealand, Japan, South Korea and the Philippines as Navoban, but is not available in the U.S. It is also available from Novell Pharmaceutical Laboratories and marketed in several Asian countries as Setrovel.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets 5 HT Receptor/Serotonin Receptor 

Structure

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