Vidarabine

  • Chemical Properties
CAS No. 5536-17-4 Cat. No. BCP27778
Name Vidarabine
Synonyms Vira A; Vira-A; ViraA; Ara-A; Ara A; Arabinofuranosyladenine;Adenine Arabinoside; 9-beta-Arabinofuranosyladenine;
Formula C10H13N5O4 M. Wt 267.25
  • Biological Activity
Description Vidarabine is an antiviral drug which is active against herpes simplex and varicella zoster viruses. The drug was originally intended as an anti-cancer drug. The anti-viral activity of vidarabine was first described by M. Privat de Garilhe and J. De Rudder in 1964. It was the first nucleoside analog antiviral to be given systemically and was the first agent to be licensed for the treatment of systematic herpes virus infection in humans. It was University of Alabama at Birmingham researcher and physician Dr. Richard Whitley in 1976 where the clinical effectiveness of vidarabine was first realized, and vidarabine was used in the treatment of many viral diseases.
Pathways Microbiology/Virology Cell Cycle/DNA Damage 
Targets Antimetabolite HSV 

Structure

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