Glipizide

  • Chemical Properties
CAS No. 29094-61-9 Cat. No. BCP09195
Name Glipizide
Synonyms CP 28720; K 402;CP28720; K402;CP-28720; K-402;
Formula C21H27N5O4S M. Wt 445.54
  • Biological Activity
Description Glipizide is a short-acting, second-generation, blood-glucose-lowering agent belonging to the sulfonylurea class that increases the release of endogenous insulin from β-cells by blocking potassium channels. The drug-formulated version of Glipizide, marketed as Glucotrol or under generic label, is most commonly prescribed to lower blood sugar levels in type 2 diabetes. Glipizide is rapidly absorbed, has a very quick onset of action and a short half-life. This agent is extensively metabolized in the liver and the metabolites as well as the unchanged form are excreted in the urine.
Pathways Ion Channel/Membrane Transporter 
Targets Potassium Channel 

Structure

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