GIT 27
| CAS No. | 6501-72-0 | Cat. No. | BCP09284 |
| Name | GIT 27 | ||
| Synonyms | 4,5-Dihydro-3-phenyl-5-isoxazoleaceticacid; VGX-1027; | ||
| Formula | C11H11NO3 | M. Wt | 205.21 |
| Description | Orally active immunomodulatory agent that primarily targets macrophages. Inhibits TNF-α secretion via interference of macrophage toll-like receptor (TLR) 4 and TLR 2/6 signaling pathway. Reduces secretion of pro-inflammatory cytokines IL1-β, IL-10 and IFN-γ. Antidiabetogenic and prevents IL-β and IFN-γ-induced pancreatic islet cell death in vitro | ||
| Pathways | Others Pathway | ||
| Targets | Interleukin Related | ||
Structure
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