Z-JIB-04

  • Chemical Properties
CAS No. 199596-24-2 Cat. No. BCP13580
Name Z-JIB-04
Synonyms JIB-04 Z-isomer;NSC 693627;NSC-693627;NSC693627;
Formula C17H13ClN4 M. Wt 308.76
  • Biological Activity
Description JIB-04 Z-isomer, also known as NSC 693627, is an isomer of JIB-04. JIB-04 is a Jumonji histone demethylase inhibitor. JIB-04 selectively blocks cancer cell growth in vitro and diminishes tumor growth in H358 and A549 mouse xenograft models in vivo. JIB-04 can prolong survival in a mouse model of breast cancer.
Pathways Epigenetics 
Targets Histone Demethylase 

Structure

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