Lubiprostone

  • Chemical Properties
CAS No. 136790-76-6 Cat. No. BCP14113
Name Lubiprostone
Synonyms Amitiza;RU-0211;SPI-0211;RU0211;SPI0211;RU 0211;SPI 0211;
Formula C20H32F2O5 M. Wt 390.46
  • Biological Activity
Description Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. These secretions soften the stool, increase motility, and promote spontaneous bowel movements (SBM).
Pathways Ion Channel/Membrane Transporter 
Targets Chloride Channel 

Structure

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