SBE 13 hydrochloride
| CAS No. | 1052532-15-6 | Cat. No. | BCP23836 |
| Name | SBE 13 hydrochloride | ||
| Synonyms | SBE13; SBE 13; SBE13; SBE-13 HCl;SBE13 Hydrochloride ;SBE-13 Hydrochloride; | ||
| Formula | C24H28Cl2N2O4 | M. Wt | 479.4 |
| Description | SBE13 Hydrochloride is a potent and selective Plk1 inhibitor, with an IC50 of 200 pM; poorly inhibits Plk2 (IC50>66 μM) or Plk3 (IC50=875 nM).SBE-13 is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μ M for PLK1, PLK3 and PLK2 respectively). | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PLK | ||
Structure
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